Tuesday, May 25, 2021

Coronavirus: vaccination doesn't eliminate the risk of getting COVID-19

We know that getting vaccinated does not totally eliminate the possibility of getting COVID-19. I think we're getting some good evidence on just how effective the vaccines are in real world case studies versus clinical trials. Unfortunately, many of these real world case studies are occurring in nursing homes. 

The New York Times (Apr 21) has an April example from Kentucky:

An unvaccinated health care worker set off a Covid-19 outbreak at a nursing home in Kentucky where the vast majority of residents had been vaccinated, leading to dozens of infections, including 22 cases among residents and employees who were already fully vaccinated, a new study reported Wednesday.

Most of those who were infected with the coronavirus despite being vaccinated did not develop symptoms or require hospitalization, but one vaccinated individual, who was a resident of the nursing home, died, according to the study released by the Centers for Disease Control and Prevention.

Altogether, 26 facility residents were infected, including 18 who had been vaccinated, and 20 health care personnel were infected, including four who had been vaccinated. Two unvaccinated residents also died.

The article goes on to say that the effectiveness rate for residents was at 66%, but increased to 86% when focusing on symptomatic illness.

Another example came about in March. A Canadian nursing home had a similar outbreak. Yahoo via CBC (Mar 15):

Twenty-three cases of COVID-19 have been identified in an outbreak at a long-term care centre in Kelowna where over 80 per cent of residents were vaccinated, and 65 per cent of staff.

[Provincial Health Officer Dr. Bonnie Henry] has previously reported that some of the people who tested positive at Cottonwoods had already received two doses of the vaccine.

The article doesn't state how many of the 23 cases were associated with those who had been fully vaccinated. 

Then there is the case with the New York Yankees. Yahoo (May 13) reports:

The New York Yankees announced on Thursday that shortstop Gleyber Torres has tested positive for COVID-19.

He's the eighth person in the organization to return a positive test this week. The other positive tests were among members of the coaching and support staff. The Yankees previously announced that pitching coach Matt Blake, third base coach Phil Nevin and first base coach Reggie Willits tested positive in addition to four unidentified members of the team's support staff.

Luckily, the article states that 7 of the 8 are asymptomatic, but then will they stay asymptomatic? The article goes on to report that are were vaccinated with the Johnson & Johnson vaccine.       

I think these examples could also apply to other real life situations as the United States begins to open up more widely. What about packed bars? Those going to bars won't be wearing masks. How example are you supposed to drink your alcoholic drink of choice? I could also see this at smaller music venues where people are packed onto the floor and many of those attending will also be drinking while watching the show.

Hopefully, such outbreaks remain limited in scale and contact tracing is easy to accomplish. 

Finally, a more anecdotal example comes from hard hit India. New York Times (Apr 28):

At Sir Ganga Ram hospital, the 37 doctors who became infected after immunization had received their first dose of the AstraZeneca vaccine between late January to early February and then their second dose four to six weeks after that. The hospital employs about 500 doctors.

Dr. Shad, the cardiac surgeon, was reluctant to jump to conclusions about variants breaking through the immunizations. “I don’t think anyone has the serological data” to answer that, he said.


Need to keep an eye on this one as it might be related to India's "double mutant" variant.

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